Amanda DeGuio

Case Information:

Amanda DeGuio, 24, vanished from her home in Drexel Hill, Pennsylvania, in June 2014. A mother of two, Amanda had recently returned from a family trip to Disney World. While she appeared optimistic about the future, she disappeared just days later, leaving her children and all her belongings.

On the morning of June 3, 2014, Amanda’s mother saw her in her bedroom for the last time. When the family returned later that afternoon, Amanda was gone, beginning a mystery that has now spanned over a decade.

Case Details:

Amanda is described as a “social, girlie girl” who once dreamed of becoming a pediatric nurse. Her life took a tragic turn following a diagnosis of a flesh-eating disease after the birth of her first daughter. This medical crisis required multiple surgeries and led to a subsequent addiction to pain medication.

By the time she vanished, Amanda was struggling with heroin addiction and bipolar disorder. Because she left without her cell phone, credit cards, or extra clothing—and did not drive—investigators remain baffled as to how she left the residence or who she may have been with.

Timeline of Events:

The last confirmed sighting of Amanda DeGuio was on the morning of June 3, 2014. While she had been known to go “off the grid” for short periods in the past, she had never left her children behind for an extended time.

By late August 2014, her family realized this was not a typical absence and officially filed a missing persons report. Despite her history, there were no signs of a struggle or foul play discovered inside the family home.

Investigation:

The Upper Darby Police Department has maintained an active investigation, even re-opening a full review of the case in early 2021. Authorities have explored potential links to the local sex trade, as Amanda had previously been identified in online escort advertisements.

Investigators have conducted numerous interviews and surveyed areas Amanda DeGuio was known to frequent, including the Overbrook and Kensington sections of Philadelphia. While several arrests were made in connection to the escort ads, no information regarding Amanda’s whereabouts was uncovered.

Community Response:

The Drexel Hill and Upper Darby communities have remained dedicated to finding Amanda. Her sister, Nicole, and mother, Joanne, have been tireless advocates, organizing searches and distributing flyers throughout the Delaware County area.

The FBI has also joined the effort, listing Amanda on their “Wanted” page for missing persons. A significant reward of $10,000 has been established for any information that leads to a breakthrough in the case.

Family Statements:

Joanne DeGuio continues to raise Amanda’s two daughters, stating that the children are what keep her going. The family maintains that while Amanda faced personal demons, she was a loving mother who wouldn’t have abandoned her family by choice.

The family has expressed frustration over the years with the “stigma” often attached to cases involving addiction. They continue to urge the public to look past the labels and see the daughter, sister, and mother who is still missing.

Physical Appearance:

Amanda DeGuio is a white female, 5’2” tall, weighing approximately 110–120 pounds. She has blue eyes and brown hair, though she was known to frequently change her hairstyle or wear wigs.

She has several identifying marks, including a diagonal surgical scar on her abdomen. Her tattoos include:

• Lips on her right buttock.
• The Italian boot and the word “Tommy” on her right torso.
• The letters “MF” on the inside of her lower lip.
• The initials “SC” on her left ring finger.

Current Status:

As of March 2026, the disappearance of Amanda DeGuio remains an open investigation. While police have categorized the file as a “death investigation” due to the length of time she has been gone, the family still holds onto hope for a definitive answer.

Amanda may be using the aliases Adrianna, Gianna, or Stacy. She is known to frequent Upper Darby, Clifton Heights, and the Overbrook section of Philadelphia.

Contact Information:

If you have any information regarding the whereabouts of Amanda DeGuio, please contact the Upper Darby Police Department at (610) 734-7693 or Pennsylvania Crime Stoppers at 1-800-4PA-TIPS. Your tip could be the one that brings Amanda home to her daughters.

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